# Senior Clinical Trial Manager Remote from[USA](https://jobicy.com/job-region/usa.md)Annual salary Undisclosed Salary information is not provided for this position. Check our [Salary Directory](https://jobicy.com/salaries.md) to estimate the average compensation for similar roles.Department [Project Management](https://jobicy.com/categories/project-management.md) Employment type Full Time, Job posted22 Jul 2026Apply before22 Aug 2026Experience level Senior Views / Applies 57 / 4 [About company](https://jobicy.com/company/natera.md) * Share About [Natera](https://jobicy.com/company/natera.md) Transforming patient care through genetic testing and precision medicine. [Biotechnology](https://jobicy.com/company-category/biotechnology.md) * 2004 Actively Hiring Verified job posting This job post has been [manually reviewed](https://jobicy.com/tools/help-center/employee/how-does-jobicy-verify-the-legitimacy-of-remote-job-listings.md) for authenticity and compliance. ### AI Summary The Senior Clinical Trial Manager will oversee all aspects of oncology clinical trials, including study design, protocol implementation, site monitoring, and recruitment. This role requires collaboration with clinical operations, R&D, and scientific communications teams to ensure robust trial execution. Responsibilities include managing budgets, training vendors and investigators, and mentoring junior staff. The ideal candidate has 5-8 years of clinical research experience with a focus on FDA regulations and oncology. Natera offers a competitive compensation package and the opportunity to work in a fast-paced, collaborative environment. ### Role DNA Job Complexity Easy Hard Pace & Pressure Relaxed Fast-paced Autonomy Level Guided Full Ownership Communication Load Independent Highly Collaborative AI Insight The role requires managing complex oncology trials independently but within established regulatory frameworks, resulting in a moderate difficulty level of 3. ### Salary Analysis Median Market Rate $148,400US Market $120k – 180k 0 $198k AI Insight The offered salary range of $131,900–$164,900 is competitive for a senior clinical trial manager role, aligning well with the US market median of $150,000. The position provides a strong compensation package for experienced professionals in oncology. ### Core Skills Required [Clinical Trial Management](https://jobicy.com/jobs?search_keywords=Clinical+Trial+Management.md) [Oncology](https://jobicy.com/jobs?search_keywords=Oncology.md) [FDA Regulations](https://jobicy.com/jobs?search_keywords=FDA+Regulations.md) [Protocol Design](https://jobicy.com/jobs?search_keywords=Protocol+Design.md) [Site Monitoring](https://jobicy.com/jobs?search_keywords=Site+Monitoring.md) [Budget Management](https://jobicy.com/jobs?search_keywords=Budget+Management.md) [CRO Management](https://jobicy.com/jobs?search_keywords=CRO+Management.md) [Cross-functional Collaboration](https://jobicy.com/jobs?search_keywords=Crossfunctional+Collaboration.md) [Mentoring](https://jobicy.com/jobs?search_keywords=Mentoring.md) [Regulatory Compliance](https://jobicy.com/jobs?search_keywords=Regulatory+Compliance.md) ### Cover Letter Sample I am writing to express my strong interest in the Senior Clinical Trial Manager position at Natera. With over 7 years of clinical research experience and a proven track record of managing oncology trials independently, I am confident in my ability to contribute to your team. My background includes designing protocols, managing budgets, and ensuring compliance with FDA regulations, all of which align with the responsibilities outlined in the job description. I have successfully led cross-functional teams and mentored junior staff, fostering a collaborative and efficient work environment. Natera's commitment to advancing cell-free DNA testing in oncology is inspiring, and I am eager to bring my expertise in site monitoring and vendor management to support your clinical programs. Thank you for considering my application. I look forward to the opportunity to discuss how my skills and experience can drive the success of Natera's clinical trials. Copy ### Sample Interview Questions Describe a complex oncology trial you managed from start to finish. What were the key challenges and how did you overcome them?I managed a Phase II trial for a novel immunotherapy. Key challenges included slow patient enrollment and complex regulatory requirements. I mitigated enrollment issues by expanding site networks and improving patient recruitment strategies. For regulations, I worked closely with the regulatory team to ensure all submissions were accurate and timely, and I implemented a robust tracking system.How do you ensure compliance with FDA regulations during a clinical trial?I ensure compliance by staying updated on FDA guidelines, conducting regular audits, and training site staff on protocol requirements. I also implement quality control measures, such as reviewing documents for accuracy and maintaining detailed records. Additionally, I collaborate with regulatory affairs to address any changes promptly.How would you handle a situation where a CRO is not meeting performance expectations?I would first communicate with the CRO to identify the root causes and set clear performance benchmarks. If issues persist, I would escalate to senior management and consider implementing corrective action plans or transitioning to a new vendor. Throughout, I document all interactions and maintain open lines of communication.Describe your experience with budgeting and managing clinical trial finances.I have managed budgets for multiple trials, ensuring costs align with allocated funds. I track expenses using financial tools, negotiate vendor contracts, and provide regular financial reports. I also work with finance to forecast future costs and adjust budgets as needed.How do you mentor junior clinical operations staff?I mentor by setting clear expectations, providing hands-on training, and offering constructive feedback. I encourage them to take ownership of tasks while being available for guidance. I also create development plans to help them build skills in trial management and regulatory compliance. POSITION SUMMARY: The Senior Clinical Trial Manager will be responsible for managing all aspects of clinical trials in the field of Oncology. The Clinical Trial Manager should have experience in managing all aspects of the trials independently, including study design, protocol implementation, site monitoring, and recruitment site management. Natera is dedicated to robust clinical trial design and execution, as demonstrating test ability and performance is essential to Natera’s reputation and integrity. The candidate will work closely with Natera’s clinical trials, R&D and scientific communications teams to accomplish this end. PRIMARY RESPONSIBILITIES: * Responsible for the implementation of clinical trial activities per study protocol. * Works closely with investigative site personnel, CROs, and other study vendors * Manage study contracting, budget and payment process for all clinical trial vendors including investigational sites. * Design study related documents, including but not limited to study protocol, informed consent forms, CRFs, and regulatory binders. * Train CROs, vendors, investigators and study coordinators on study protocol and relevant requirement. * Monitor and track clinical trial progress and provide status update to stakeholders. * Partner with other research and development groups to achieve deliverables. * Mentor junior clinical operations staff and supervise clinical study team. * This role works with PHI on a regular basis both in paper and electronic form and have an access to various technologies to access PHI (paper and electronic) in order to perform the job. * Employee must complete training relating to HIPAA/PHI privacy, General Policies and Procedure Compliance training and security training as soon as possible but not later than the first 30 days of hire. * Must maintain a current status on Natera training requirements. QUALIFICATIONS: * Bachelor’s degree in life sciences, or other relevant discipline required, Advanced degree preferred. * 5-8 years of clinical research experience, including at least 2-5 years of experience in managing clinical trials as a leading role. * Familiar with the FDA regulations relevant to clinical trials. * Experience in managing studies, CROs and sponsors is preferred. * Able to collaborate with the study team, cross functional team members and external collaborators KNOWLEDGE, SKILLS, AND ABILITIES: * Proficiency in MS Word, Excel and PowerPoint * Good organization and planning skills * Strong interpersonal skills and communication skills (both written and oral) * Strong leadership skills, self-motivated, adaptable to a dynamic and fast paced environment The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$131,900—$164,900 USD OUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits – Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! For more information, visit [www.natera.com](http://www.natera.com/). Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents. Link: [https://www.natera.com/notice-of-data-collection-california-residents/](https://www.natera.com/notice-of-data-collection-california-residents) Please be advised that Natera will reach out to candidates with a @[natera.com](http://natera.com/) email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes. For more information: – [BBB announcement on job scams](https://www.bbb.org/article/tips/12261-bbb-tip-employment-scams) – [FBI Cyber Crime resource page](https://www.fbi.gov/investigate/cyber) Show more [Apply now >](https://jobicy.com/jobs/149593-senior-clinical-trial-manager.md) > Annual salary information is not provided for this position. Explore salary ranges for similar roles in our [Salary Directory ›](https://jobicy.com/salaries.md) * ![Upload CV](data:image/svg+xml;base64,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) ### Upload your resume now To unlock remote work opportunities and be discovered by global employers. 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