[![Image]() Meet Jobicy Copilot — free AI autofill for job applications + remote job alerts ›](#) [All remote jobs](https://jobicy.com/jobs.md)Open role[![Natera logo](https://jobicy.com/data/server-nyc0409/galaxy/mercury/2025/06/1c3a8032-221.png)](https://jobicy.com/company/natera.md)Remote opportunity at[Natera](https://jobicy.com/company/natera.md) # Associate Director of Bioinformatics (Women’s Health and Organ Health) Review the role, location requirements, compensation details, and application process before deciding whether this opportunity fits your next career move. [Apply for this job](#job-application)[View company](https://jobicy.com/company/natera.md)Share20 Sep 2026Published37Listing views4Application actions20 Oct 2026Apply before Opportunity details ## About this role. AI SummaryThis Associate Director of Bioinformatics role leads a team developing diagnostic sequencing assays for women's health and organ health products. The position combines scientific strategy, people leadership, NGS and cell-free DNA analytics, assay optimization, and transition of research methods into regulated production workflows. The leader will partner extensively with laboratory, data science, engineering, biostatistics, quality, product, and operations teams. Success requires deep experience with diagnostic product development, clinical laboratory standards, Python-based analysis, and robust software engineering practices for bioinformatics pipelines. The role is remote within the United States and emphasizes high-impact delivery in a fast-paced environment. ## Role DNA A quick view of the complexity, pace, ownership and collaboration implied by the job description. ### Job Complexity 5/5EasyHard ### Pace & Pressure 5/5RelaxedFast-paced ### Autonomy Level 5/5GuidedFull ownership ### Communication Load 5/5IndependentCollaborative AI insightThis is a senior scientific leadership role requiring both deep technical expertise in NGS diagnostics and demonstrated experience moving research into real clinical production use. The incumbent must manage a team, set research strategy, make high-stakes scientific judgments, and coordinate complex cross-functional delivery in a regulated environment. ## Salary analysis Estimated compensation compared with the broader US market for similar roles. Estimated job medianMarket rate$184,300US market range$160k–$230k0$253k AI insightThe disclosed yearly USD salary range is $166,600 to $202,000, with a midpoint of $184,300. For a US-based Associate Director of Bioinformatics leading regulated diagnostic assay development, an estimated broader market range is approximately $160,000 to $230,000 annually; total compensation may vary based on location, leadership scope, equity, and specialized clinical diagnostics experience. ## Core skills Skills and capabilities most closely associated with this opportunity. [Bioinformatics](https://jobicy.com/jobs?search_keywords=Bioinformatics.md)[Next-Generation Sequencing](https://jobicy.com/jobs?search_keywords=Next-Generation%20Sequencing.md)[Cell-Free DNA](https://jobicy.com/jobs?search_keywords=Cell-Free%20DNA.md)[Diagnostic Assay Development](https://jobicy.com/jobs?search_keywords=Diagnostic%20Assay%20Development.md)[Clinical Diagnostics](https://jobicy.com/jobs?search_keywords=Clinical%20Diagnostics.md)[Python](https://jobicy.com/jobs?search_keywords=Python.md)[Variant Calling](https://jobicy.com/jobs?search_keywords=Variant%20Calling.md)[Multiomics](https://jobicy.com/jobs?search_keywords=Multiomics.md)[Bioinformatics Pipeline Development](https://jobicy.com/jobs?search_keywords=Bioinformatics%20Pipeline%20Development.md)[People Leadership](https://jobicy.com/jobs?search_keywords=People%20Leadership.md) Sample interview questionsDescribe a diagnostic sequencing assay or analysis method you helped move from research into clinical or production use.I would explain the clinical objective, assay and data characteristics, validation strategy, performance benchmarks, and cross-functional stakeholders involved. I would also describe how I converted the research workflow into a version-controlled, tested, monitored production pipeline and how I addressed quality, regulatory, and operational requirements. How would you evaluate a new cfDNA sequencing technology or assay chemistry against an established method? I would define intended use and acceptance criteria first, then design a representative study covering analytical sensitivity, specificity, precision, reproducibility, failure modes, coverage, error profiles, and workflow feasibility. I would compare results against established benchmarks, assess operational and cost implications, and make a recommendation supported by statistical evidence and documented limitations. How do you balance exploratory bioinformatics research with the need for reliable production software? I separate rapid prototyping from productionization while maintaining clear handoff criteria. Exploratory work can move quickly, but production candidates require reproducible environments, version control, automated tests, code review, documentation, benchmarking, monitoring, and defined ownership before release. How would you lead and develop a team of bioinformatics scientists working across multiple research priorities? I would establish a visible roadmap tied to product and scientific priorities, clarify decision rights and success metrics, and regularly review progress and risks. I would match projects to individual development goals, provide technical and career coaching, and create routines for peer review, knowledge sharing, and cross-functional alignment. How do you communicate a complex finding, such as an assay performance limitation, to non-bioinformatics stakeholders? I start with the decision that needs to be made and state the practical impact in plain language. I then present the key evidence, uncertainty, risks, and recommended next steps using focused visuals and an appropriate technical appendix, ensuring stakeholders understand both the implication and the path forward. Natera is seeking an Associate Director to lead a team of Bioinformatics Scientists in our Women’s Health and Organ Health research organization. You will oversee the scientific planning and execution of research and assay-development of diagnostic projects, and you will be responsible for creating production-ready pipeline components. You will manage your team and its professional growth, the research strategy behind new product development, and the handoff of research work into production. The role calls for deep experience in algorithm and assay development, NGS data processing across multiple modalities, and the full life cycle of diagnostic product research and development in a regulated (CLIA) setting. You will evaluate new technologies and NGS assays, implement methods to optimize performance, and help define the product profile from a bioinformatics perspective, with input from R&D, Product, and Laboratory Directors. ### Primary Responsibilities: Team Leadership and Development: Lead and mentor a team of Bioinformatics Scientists. Own their professional growth, their responsibilities, and the standard the team holds itself to. Research Strategy: Own the research strategy behind new product development, from scoping through execution, working with cross-functional stakeholders on what the team takes on and in what order. Assay Science: Lead bioinformatics analysis for assay development and optimization, and troubleshoot experiments alongside laboratory scientists. This spans multi-omic approaches including methylation and fragmentomics and other cell-free DNA (cfDNA) derived features. It also spans short-read and long-read sequencing and both hybrid-capture and amplicon target enrichment. Study Design and Data Quality: Partner with laboratory teams on study design at the research and feasibility stage, covering new technology assessment, optimization, and performance determination. Make sure the resulting data holds up before anyone builds on it. Analysis Method Improvement: Advise and prototype improvements to analysis pipelines, including variant detection, quality control, and modality-specific processing: methylation calling, fragment-size and end-motif analysis, error suppression for deep targeted panels, and structural-variant calling. Production Readiness and Handoff: Move research prototypes into stable production workflows. Hold the team to software engineering practice, including version control, testing, continuous integration and delivery, and containerization. Automate the routine parts of research data management, pipeline execution, and reporting so the team’s time goes to science. Ways of Working: AI is a routine part of the work here. As the leader of this team you set what correct use looks like: what an agent may conclude on its own, and what requires a scientist to sign off. We do not screen for prior experience with these tools, and many strong candidates come from environments where they were restricted; we provide the tooling and the ramp time. Cross-functional Partnership: Work with data science, molecular biology, pipeline engineering, biostatistics, quality assurance, and laboratory operations on new products and on the transition of research work into production. Act as the subject-matter expert those groups come to, and explain findings and the roadmap clearly at every level of the company. ### What success looks like after a year: * The team has a research roadmap you own, and progress against it is visible outside the team. * You independently advise and guide research strategies in cross functional settings. * New analysis methods from your team are implemented within production code and demonstrate expected performance on benchmark studies.. * You and team members become trusted experts that other functions direct their hard questions to, and can independently support decision making. * AI agent-assisted work is normal on the team, with a standard for it that you set. ### Qualifications: * Ph.D. in Bioinformatics, Computational Biology, Computer Science, Mathematics, Engineering, Biostatistics, or a related field. (An M.S. with equivalent experience considered). * 7+ years in bioinformatics, including 3+ years leading scientists and working across functions. * Demonstrated ownership of a team that took scientific research into real clinical use, not only to a result. * Demonstrated experience developing or scientifically guiding diagnostic sequencing assays. ### Knowledge, Skills, and Abilities: ### What we are screening for * Deep expertise in next-generation sequencing analysis: hybrid-capture or amplicon-based target enrichment designs, sequencing quality control, secondary analysis, and variant calling. * Experience with cell-free DNA sequencing and other omics data, especially in a diagnostics setting. Preferred to have some exposure to multiomics types : methylation, fragmentomics, or related cfDNA signals. * Working knowledge of how a diagnostic product moves through development in a regulated, accredited setting, including the practices and standards that apply. * Strong Python, programming, and data analysis skills. * Fluency in exploratory data analysis and visualization on complex data sets, and the ability to translate findings into actionable recommendations. * Understanding of sequencing workflows from sample extraction through the instrument, deep enough to tell a biology problem from an analysis problem. * A demonstrated record of assessing a new platform, assay chemistry or method against established benchmarks.. * Clear communication of technical detail to people who do not share your background. * The ability to run several objectives and timelines at once without close supervision. ### Strong candidates may also have * Long-read sequencing (PacBio HiFi, Oxford Nanopore) in addition to short-read (Illumina). * R, shell scripting, or Java. * Cloud computing (AWS, GCP) and workflow orchestration (Snakemake, WDL, Nextflow, Cromwell). * Containerization (Docker, Kubernetes) for reproducible, production-grade analyses. * A record of conference presentations or peer-reviewed publication. * A desire to work in a fast-paced environment where a small team has high impact. The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations. Remote USA $166,600—$202,000 USD OUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits – Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! For more information, visit [www.natera.com](http://www.natera.com/). Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents. Link: [https://www.natera.com/notice-of-data-collection-california-residents/](https://www.natera.com/notice-of-data-collection-california-residents) Please be advised that Natera will reach out to candidates with a @[natera.com](http://natera.com/) email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes. For more information: – [BBB announcement on job scams](https://www.bbb.org/article/tips/12261-bbb-tip-employment-scams) – [FBI Cyber Crime resource page](https://www.fbi.gov/investigate/cyber) Show more [Apply now >](https://jobicy.com/jobs/153751-associate-director-of-bioinformatics-womens-health-and-organ-health.md) * ![Upload CV](data:image/svg+xml;base64,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) ### Upload your resume now To unlock remote work opportunities and be discovered by global employers. 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