[All remote jobs](https://jobicy.com/jobs.md)[![Precision Medicine Group logo](https://jobicy.com/data/server-nyc0409/galaxy/mercury/2025/06/f1277044-221.jpg)](https://jobicy.com/company/precision-medicine-group.md)[Precision Medicine Group](https://jobicy.com/company/precision-medicine-group.md) # Principal/Senior Clinical Data Scientist Review the role, location requirements, compensation details, and application process before deciding whether this opportunity fits your next career move. [Apply for this job](#job-application)[View company](https://jobicy.com/company/precision-medicine-group.md)ShareRemote from[UK](https://jobicy.com/job-region/uk.md), [Spain](https://jobicy.com/job-region/spain.md), [Romania](https://jobicy.com/job-region/romania.md)+4 more, [Poland](https://jobicy.com/job-region/poland.md), [Hungary](https://jobicy.com/job-region/hungary.md), [Slovakia](https://jobicy.com/job-region/slovakia.md), [Serbia](https://jobicy.com/job-region/serbia.md)SalaryUndisclosedDepartment[Healthcare & Medical](https://jobicy.com/categories/healthcare.md)EmploymentFull TimeExperienceSeniorPublished28 Oct 2026Apply before27 Nov 2026Listing views37Application actions1Application toolkit ## Make your next move. Prepare your resume, explore your fit, and draft a cover letter for this opportunity. AI Summary ## The role, at a glance. This senior clinical science role leads clinical data review activities for oncology, rare disease, and autoimmune development programs from study start-up through database lock. The hire applies therapeutic-area expertise to participant-level and aggregate data review, query management, data cleaning, eCRF design, RBQM, and medical data review meetings. It requires at least eight years of clinical research experience, recent oncology experience, and prior leadership experience. The position works independently in a global cross-functional environment while managing quality, delivery timelines, budgets, and junior team development. ## Role DNA A quick view of the complexity, pace, ownership and collaboration implied by the job description. ### Job Complexity 5/5EasyHard ### Pace & Pressure 4/5RelaxedFast-paced ### Autonomy Level 5/5GuidedFull ownership ### Communication Load 5/5IndependentCollaborative AI insightThis is a principal/senior-level role requiring deep, current oncology expertise and broad command of clinical trial operations, data standards, and regulatory expectations. The incumbent must independently resolve complex clinical data issues while leading stakeholders across global studies. ## Salary analysis Estimated compensation compared with the broader US market for similar roles. Estimated job median (per year)Market rate$145,000US market range (per year)$120k–$175k0$192.50k AI insightThe yearly pay period is inferred from the job context; it was not explicitly stated by the employer. No employer compensation was disclosed. Annual pay cadence is inferred from the senior full-time clinical research role; the displayed figures are estimated USD annual market compensation for a comparable US-market Principal/Senior Clinical Data Scientist role. ## Core skills Skills and capabilities most closely associated with this opportunity. [Oncology clinical research](https://jobicy.com/jobs?search_keywords=Oncology%20clinical%20research.md)[Clinical data review](https://jobicy.com/jobs?search_keywords=Clinical%20data%20review.md)[Clinical data cleaning](https://jobicy.com/jobs?search_keywords=Clinical%20data%20cleaning.md)[Electronic Data Capture](https://jobicy.com/jobs?search_keywords=Electronic%20Data%20Capture.md)[eCRF design](https://jobicy.com/jobs?search_keywords=eCRF%20design.md)[Risk Based Quality Management](https://jobicy.com/jobs?search_keywords=Risk%20Based%20Quality%20Management.md)[ICH-GCP](https://jobicy.com/jobs?search_keywords=ICH-GCP.md)[FDA regulatory guidance](https://jobicy.com/jobs?search_keywords=FDA%20regulatory%20guidance.md)[RECIST 1.1](https://jobicy.com/jobs?search_keywords=RECIST%201.1.md)[CTCAE](https://jobicy.com/jobs?search_keywords=CTCAE.md)[Query management](https://jobicy.com/jobs?search_keywords=Query%20management.md)[Clinical trial operations](https://jobicy.com/jobs?search_keywords=Clinical%20trial%20operations.md)[Medical data review](https://jobicy.com/jobs?search_keywords=Medical%20data%20review.md)[eTMF management](https://jobicy.com/jobs?search_keywords=eTMF%20management.md)[Clinical data visualization](https://jobicy.com/jobs?search_keywords=Clinical%20data%20visualization.md) Sample interview questionsHow do you approach a holistic participant-level data review for an oncology study?I begin with the protocol, schedule of assessments, eligibility criteria, and disease-specific standards such as RECIST and CTCAE. I review data longitudinally across domains to identify inconsistencies, safety signals, missing information, and protocol deviations, then document clinically meaningful queries and follow them through resolution with the appropriate study functions. Describe how you have used oncology criteria such as RECIST 1.1 or CTCAE in data review. I apply the criteria to assess whether recorded disease assessments and adverse-event grading are internally consistent, complete, and aligned with protocol requirements. When findings are unclear, I compare source-aligned data points across visits and collaborate with medical monitors, sites, and data management to resolve discrepancies without making unsupported assumptions. How would you contribute to risk-based quality management on a clinical trial? I would identify critical data and processes, monitor trends through data review outputs and team feedback, and assess their potential impact on participant safety and study endpoints. I would bring prioritized risks to cross-functional review meetings, define practical mitigation actions, and monitor whether the actions reduce the observed risk. How do you manage competing deadlines across multiple global studies? I establish a clear plan with milestones, dependencies, owners, and escalation thresholds for each study. I prioritize participant safety, database-lock-critical activities, and high-impact risks, communicate capacity constraints early, and maintain transparent trackers so stakeholders understand progress and decisions. What is your leadership approach when mentoring junior clinical science team members? I pair structured training on protocols, therapeutic-area standards, and review processes with supervised practical work. I provide specific feedback on clinical reasoning and documentation, encourage questions and independent analysis, and gradually increase ownership while remaining available for escalation on complex issues. Opportunity details ## About this role. Position Summary: The Principal/Senior Clinical Scientist is responsible for leading the clinical science function across assigned Oncology, Rare Diseases, and/or Autoimmune clinical development programs, from study start-up through database lock, in alignment with project scope, timelines, and quality expectations. Applicants must have Oncology experience (see Minimum Required Qualifications). In this role, you will provide scientific and indication-specific expertise to support the collection, review, and interpretation of clinical trial data. Working as a key member of Precision for Medicine’s cross-functional data review team, you will apply clinical knowledge and scientific insight to identify, evaluate, and resolve data issues, manually (not just programmed exclusion listings outputs) while also leveraging data review tools and platforms, ensuring clinically accurate and high-quality data while protecting participant safety. As a subject matter expert, you will leverage current clinical practice guidelines, standards of care, and disease-area expertise to support complex, scientific and clinical data review and data cleaning activities. You will play an active role in supporting study deliverables and collaborating with internal and external study team members to ensure successful study execution within scope, budget, and timelines. Key Responsibilities: * Serve as a functional team lead, implementing Clinical Science services per study scope of work on assigned projects from study start through database lock ensuring delivery of high-quality outcomes within agreed timelines and budgets. * Perform holistic individual participant data review, and aggregate participant data review, utilizing a combination of Precision’s proprietary and non-proprietary data review tools and platforms, while applying clinical and scientific judgment based on therapeutic area and indication specific expertise to support data capture, data review and interpretation, query management, and clinically relevant data cleaning activities. * Serve as the scientific and clinical data subject matter expert for study teams, guiding eCRF design, data capture requirements, edit checks, completion guidelines, EDC UAT, and ongoing clinical data review and cleaning to ensure protocol-compliant, high-quality data as studies progress. * Support Risk Based Quality Management (RBQM), identifying and addressing study risks, trends and issues, while partnering with cross-functional teams participating in the risk review processes and meetings. * Collaborate with Medical Monitoring including oversight of Medical Monitor review of participant data and data review findings. * Provide protocol review from a scientific operational perspective. * Working knowledge of Oncology and clinical research standard criteria (e.g.: CTCAE, ASTCT, RECIST 1.1., Lugano, ICANS, etc.). * Support Project & Financial Management invoicing and out of scope management. * Collaborate with Clinical Science management regarding resource needs. * Oversee &/or develop and maintain Clinical Science project related plans, guidelines, and trackers, programming specifications for data review tools/outputs, etc. * Ensure applicable eTMF documentation related to Clinical Science is maintained accurately. * Participate in internal and external study-specific team meetings &/or presentations as applicable including facilitating, coordinating and managing Medical Data Review Meetings. * Contribute to study-level strategy, data review processes, and continuous improvement initiatives. * Support business development needs (e.g.: bid defense meeting attendance/presentations, etc.). * May conduct review of Table, Figure & Listings (TLFs) &/or clinical study reports (CSRs). Qualifications: Minimum Required: * Bachelor’s degree or equivalent combination of education/experience in science or health-related discipline with proficiency in medical terminology * Minimum of 8 years of clinical research experience or proven competencies for this position * Minimum of 3 years Oncology experience, must have been within the past 1.5 years * Minimum of 1 year of leadership experience Other Required: * High Proficiency with Microsoft Office Products (Outlook, Word, Excel, PowerPoint, Teams, OneNote). * Excellent organization skills, attention to high quality and detail, and a customer service demeanor, communication and interpersonal skills to effectively interface with others in a team setting and written and oral including presentations of data, issues, trends, escalations, etc.. * Professional use of the English language; both written and oral * Ability to occasionally travel domestically and internationally including overnight stays (up to approximately 25%). Preferred: * Medical related degree, RN, OCN, RPH, PharmD, etc. * Strongly preferred: Experience with Electronic Data Capture (EDC) systems * Database build experience * On-site experience (nurse, study coordinator, etc.), monitoring, &/or data review experience * Experience with data visualization platform(s)/software(s) as data review tools * Experience in phase I, II & III studies and global studies Skills & Competencies: * Demonstrates highly advanced knowledge in oncology & medical terminology with ability to apply knowledge to clinical trial data including the application of disease assessment criteria, standards of care, grading criteria, etc. in a clinical research setting * Desire to continually learn and keep up to date on medical and indication-specific standards of care with the ability to self-research and educate, results oriented, exhibiting self-motivation and reliably, with the ability to work remotely while independently lead, support and inspire excellence. * Demonstrates scientific curiosity and an investigative mindset, with the ability to identify atypical data patterns, formulate hypotheses, from a scientific and clinical focus, and drive appropriate follow-up actions. * Working knowledge of FDA & ICH-GCP, relevant SOPs & regulatory guidance with a well-rounded knowledge of the entire clinical trial process and working understanding of clinical research functional departments. * Ability to independently manage the Clinical Science operational function in a global, cross-functional environment with awareness of appropriate escalation. * Excellent time management, negotiation, critical thinking, decision making, listening, analytical & conflict management skills with the ability to strategically plan & apply effective risk management. * Demonstrates ability to adjust to multiple demands & shifting priorities. * Demonstrates ability to mentor, coach, and develop junior team members while fostering a collaborative learning environment. * Ability to apply financial management skills at the functional area project level. * Excellent presentation, verbal & written communications skill Any data provided as a part of this application will be stored in accordance with our [Privacy Policy.](https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.precisionmedicinegrp.com%2Fprivacy-policy%2F&data=05%7C01%7Czeta.larcon%40precisionmedicinegrp.com%7Cb58fe8b0c3ea4dd2e79d08db5bd09a25%7Cb71ff3f628164ca8a9b938f820f91ad1%7C0%7C0%7C638204723732367131%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=9DgboiHTFPrNYVhdKhyfdwVyNYwUvZbP%2FroLdWIIfxw%3D&reserved=0) For CA applicants, please also refer to our [CA Privacy Notice](https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.precisionmedicinegrp.com%2Fca-applicants-privacy-notice%2F&data=05%7C01%7Czeta.larcon%40precisionmedicinegrp.com%7Cb58fe8b0c3ea4dd2e79d08db5bd09a25%7Cb71ff3f628164ca8a9b938f820f91ad1%7C0%7C0%7C638204723732367131%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=tfAqqMZsG%2B11IchL45HFFVbfECCkYqQpNr0PQxrMFJU%3D&reserved=0). Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law. If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at [myHR@precisionmedicinegrp.com](mailto:myHR@precisionmedicinegrp.com). Recruitment Fraud Warning: Please be aware that fraudulent individuals and websites may impersonate Precision Medicine Group or its affiliates and attempt to obtain personal, financial, or banking information through fake job postings or employment offers. Precision Medicine Group will never request payment, banking details, or other sensitive financial information as part of the recruitment process. If you believe you have been targeted by a recruitment scam, we encourage you to report the incident to your local law enforcement authorities, consumer protection agency, or relevant cybercrime reporting organization in your country. Please also notify us at [myHR@precisionmedicinegrp.com](mailto:myHR@precisionmedicinegrp.com) so we can investigate and take appropriate action. Candidates must be legally authorized to work in the country of employment without employer sponsorship. Show more [Apply now >](https://jobicy.com/jobs/157558-principal-senior-clinical-data-scientist.md) > Annual salary information is not provided for this position. 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