[All remote jobs](https://jobicy.com/jobs.md)[![Natera logo](https://jobicy.com/data/server-nyc0409/galaxy/mercury/2025/06/1c3a8032-221.png)](https://jobicy.com/company/natera.md)[Natera](https://jobicy.com/company/natera.md) # Manager of Statistical Programming Review the role, location requirements, compensation details, and application process before deciding whether this opportunity fits your next career move. [Apply for this job](#job-application)[View company](https://jobicy.com/company/natera.md)ShareRemote from[USA](https://jobicy.com/job-region/usa.md)SalaryUSD 132k–165,350 / yrDepartment[Data Science & Analytics](https://jobicy.com/categories/data-science.md)EmploymentFull TimeExperienceSeniorPublished2 Nov 2026Apply before2 Dec 2026Listing views46Application actions1Application toolkit ## Make your next move. Prepare your resume, explore your fit, and draft a cover letter for this opportunity. AI Summary ## The role, at a glance. Natera is seeking a Manager of Statistical Programming to lead clinical-trial programming deliverables for oncology diagnostic products and regulatory submissions. The role combines hands-on R development with oversight of analysis datasets, tables, listings, figures, and validated programming infrastructure. The manager may lead and develop statistical programmers while partnering with Biostatistics, Data Management, and Clinical Science. Success requires strong clinical-trial analysis experience, R package development expertise, and a thorough understanding of regulated environments including ICH, GCP, and FDA 21 CFR Part 11. ## Role DNA A quick view of the complexity, pace, ownership and collaboration implied by the job description. ### Job Complexity 5/5EasyHard ### Pace & Pressure 4/5RelaxedFast-paced ### Autonomy Level 5/5GuidedFull ownership ### Communication Load 4/5IndependentCollaborative AI insightThis is a senior, highly regulated technical leadership role involving submission-critical clinical-trial outputs and validated R infrastructure. It requires deep R expertise, clinical-programming judgment, cross-functional coordination, and potential people management. ## Salary analysis Estimated compensation compared with the broader US market for similar roles. Estimated job median (per year)Market rate$148,675US market range (per year)$130k–$180k0$198.00k AI insightThe yearly pay period is inferred from the job context; it was not explicitly stated by the employer. The employer discloses a pay range of $132,000–$165,350 USD. The annual period is inferred from the range magnitude, US location, and senior full-time statistical programming manager context. Estimated US market compensation for comparable regulated clinical statistical programming management roles is approximately $130,000–$180,000 per year. ## Core skills Skills and capabilities most closely associated with this opportunity. [R programming](https://jobicy.com/jobs?search_keywords=R%20programming.md)[Clinical trial analysis](https://jobicy.com/jobs?search_keywords=Clinical%20trial%20analysis.md)[Statistical programming](https://jobicy.com/jobs?search_keywords=Statistical%20programming.md)[Analysis datasets](https://jobicy.com/jobs?search_keywords=Analysis%20datasets.md)[TLF generation](https://jobicy.com/jobs?search_keywords=TLF%20generation.md)[R package development](https://jobicy.com/jobs?search_keywords=R%20package%20development.md)[R Shiny](https://jobicy.com/jobs?search_keywords=R%20Shiny.md)[Regulatory submissions](https://jobicy.com/jobs?search_keywords=Regulatory%20submissions.md)[FDA 21 CFR Part 11](https://jobicy.com/jobs?search_keywords=FDA%2021%20CFR%20Part%2011.md)[ICH GCP compliance](https://jobicy.com/jobs?search_keywords=ICH%20GCP%20compliance.md)[Data validation](https://jobicy.com/jobs?search_keywords=Data%20validation.md)[Programming infrastructure](https://jobicy.com/jobs?search_keywords=Programming%20infrastructure.md)[Oncology diagnostics](https://jobicy.com/jobs?search_keywords=Oncology%20diagnostics.md)[People management](https://jobicy.com/jobs?search_keywords=People%20management.md) Sample interview questionsHow have you ensured that analysis datasets and TLFs are accurate, traceable, and ready for regulatory submission?I establish documented specifications, implement independent quality-control checks, maintain traceability from source data through outputs, and retain version-controlled validation evidence. I also review outputs with biostatistics and data management early to resolve issues before final submission milestones. Describe an R package you developed or maintained for a regulated statistical programming environment. I would describe the package's purpose, controlled repository and dependency strategy, testing approach, documentation, versioning, and validation record. I would emphasize how reusable functions reduced manual work while preserving reproducibility and auditability across studies. What is your approach to leading programmers while remaining hands-on with technical delivery? I set clear ownership, quality standards, and delivery milestones, then use regular technical reviews and mentoring to remove blockers. I stay involved in high-risk design decisions and critical deliverables while giving team members meaningful responsibility for their work. How would you prepare programming deliverables for a 510(k), CTA/CDx, or PMA submission? I would align deliverables to the statistical analysis plan and submission requirements, confirm dataset and output specifications, enforce controlled-environment validation, and maintain complete documentation. I would coordinate closely with regulatory, clinical, biostatistics, and quality stakeholders to ensure consistency and inspection readiness. How would you use an R Shiny dashboard to support clinical study monitoring and data review? I would first define decisions the dashboard must support, then create validated views for enrollment, data completeness, safety or endpoint trends, and data-quality signals. Access controls, reproducible data refreshes, clear metric definitions, and user feedback would be essential for reliable use in a regulated setting. Opportunity details ## About this role. This is an exciting opportunity to participate in advancing Natera’s oncology product portfolio of cutting-edge diagnostic tests. As Manager of Statistical Programming, you will leverage your strong R programming skills and clinical trials background to contribute to the analysis and reporting of clinical trials supporting multiple regulatory submissions. ### Primary Responsibilities: * Lead and oversee statistical programming deliverables, including ADS (Analysis Datasets) and TLF (Table, Listings and Figures), ensuring data integrity and regulatory compliance with ICH, GCP, and FDA 21 CFR Part 11. * May manage a team of statistical programmers, taking responsibility for their technical and professional development, while contributing hands-on to programming work. * Act as primary programming lead for regulatory submissions (e.g., 510(k), CTA/CDx, and PMA), ensuring all deliverables meet rigorous global standards. * Maintain programming infrastructure, including R package development, validation, and maintenance in a controlled environment. * Develop R Shiny dashboards that support data review, study monitoring, and exploration of analysis results. * Promote statistical programming development and validation best practices. * Work cross-functionally with Biostats, Data Management, Clinical Science, and other functions as necessary. ### Qualifications: * Bachelor’s in Statistics, Mathematics, Computer Science, or a related field. * 5+ years of related experience, with at least 3 years of experience in Clinical Trial analysis. * At least 3 years of R programming experience, including package development. ### Knowledge, Skills, and Abilities: * Proficient in R programming, including building and maintaining packages. * Experience in analysis dataset and TLF generation. * Prior experience in NGS, genetics, and/or oncology diagnostics preferred. * Experience maintaining statistical computing environments a plus. The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations. Remote USA $132,000—$165,350 USD OUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits – Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! For more information, visit [www.natera.com](http://www.natera.com/). Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents. Link: [https://www.natera.com/notice-of-data-collection-california-residents/](https://www.natera.com/notice-of-data-collection-california-residents) Please be advised that Natera will reach out to candidates with a @[natera.com](http://natera.com/) email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes. For more information: – [BBB announcement on job scams](https://www.bbb.org/article/tips/12261-bbb-tip-employment-scams) – [FBI Cyber Crime resource page](https://www.fbi.gov/investigate/cyber) Show more [Apply now >](https://jobicy.com/jobs/158515-manager-of-statistical-programming.md) * ![Upload CV](data:image/svg+xml;base64,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) ### Upload your resume now To unlock remote work opportunities and be discovered by global employers. 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