[All remote jobs](https://jobicy.com/jobs.md)[![Jade Biosciences logo](https://jobicy.com/data/server-nyc0409/galaxy/mercury/2026/11/07b1366a60be-221.webp)](https://jobicy.com/company/jade-biosciences.md)[Jade Biosciences](https://jobicy.com/company/jade-biosciences.md) # Medical Director, Clinical Development(Nephrology) AI Summary Jade Biosciences is seeking a physician-scientist Medical Director to lead clinical development activities for nephrology programs, particularly rare and immune-mediated kidney diseases. The role directs clinical trial design, execution, medical monitoring, safety oversight, and interpretation of study data. It requires close collaboration with clinical operations, regulatory, biometrics, translational science, commercial teams, investigators, and key opinion leaders. The successful candidate will contribute to regulatory submissions, engage external stakeholders, and represent the company at scientific and industry events. This fully remote U.S.-based position includes periodic travel for team and company events.[Apply for this job](#job-application)[View company](https://jobicy.com/company/jade-biosciences.md)ShareRemote from[USA](https://jobicy.com/job-region/usa.md)SalaryUSD 270k–300k / yrDepartment[Healthcare & Medical](https://jobicy.com/categories/healthcare.md)EmploymentFull TimeExperienceDirectorPublished12 Nov 2026Apply before12 Dec 2026Listing views38Application actions1Application toolkit ## Make your next move. Prepare your resume, explore your fit, and draft a cover letter for this opportunity. Opportunity details ## About this role. About [Jade Biosciences](https://jobicy.com/company/jade-biosciences.md) Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an anti-IFN-β monoclonal antibody. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit [JadeBiosciences.com](https://url.usb.m.mimecastprotect.com/s/kwQpCrgGLMHxLkBujt66i4Vdxs?domain=globenewswire.com) and follow the Company on [LinkedIn](https://url.usb.m.mimecastprotect.com/s/S9DbCvmMP9TvMYkC5ulliQtFaR?domain=globenewswire.com). Role Overview We are seeking an experienced and mission-driven Medical Director in Clinical Development to lead and support clinical programs in nephrology, with a focus on rare or immune-mediated kidney diseases. This role is ideal for a physician-scientist who thrives in a small biotech environment where agility, cross-functional collaboration, and scientific leadership are essential. The Medical Director will play a key role in advancing Jade’s pipeline through clinical development. This newly created position will report to the Executive Medical Director of Clinical Development. This is a fully remote role and will require some travel. Key Responsibilities Clinical Development * Lead the design, execution, and oversight of clinical trials in nephrology, including protocol development, study monitoring, and data interpretation. * Serve as Medical Monitor for ongoing trials, ensuring patient safety and scientific integrity. * Collaborate with clinical operations, regulatory, and biometrics teams to ensure trial success and compliance. * Educate and advise clinical sites/investigators to support enrollment and optimal study conduct, including presenting at investigator meetings and/or site initiation visits, and serving as the medical point of contact for site staff questions about patient eligibility, and providing input into patient safety assessment and management * Provide medical expertise and support to external partners, vendors, and contractors as required to ensure smooth program execution * Communicate effectively, orally and in writing, with internal and external stakeholders regarding the assigned clinical program, including the CMO, CEO, external medical experts and others. Regulatory and Scientific Contributions * Contribute to the preparation of regulatory documents (INDs, NDAs, briefing documents, etc.). * Support interactions with regulatory authorities and ethics committees. * Stay current with scientific literature and competitive landscape in nephrology and related fields. Cross-Functional Collaboration * Partner with translational science, biomarker, and commercial teams to align clinical strategy with broader company goals. * Provide medical input into lifecycle planning and early market preparation. Stakeholder Engagement * Begin building relationships with key opinion leaders (KOLs), investigators, and advocacy groups in nephrology. * Represent the company at scientific meetings, advisory boards, and industry events. Qualifications * MD (or equivalent medical degree); board certification in nephrology strongly preferred. * 3+ years of experience as a nephrologist in academia or industry, and/or experience in nephrology clinical trials or rare disease programs. * Experience in clinical trial design, execution, and medical monitoring. * Strong clinical judgment, scientific rigor, and regulatory knowledge. * Ability to work independently and thrive in a fast-paced, matrixed environment. * Ability to manage multiple projects simultaneously and prioritize effectively in a fast-paced environment * Strong analytical, problem-solving, and decision-making skills * Excellent communication and interpersonal skills with the ability to influence and motivate cross-functional teams, manage a diverse set of stakeholders, and work closely with team leaders * High ethical standards and impeccable integrity * Exercise sound judgment in managing complex, confidential, and regulated information. Position Location This is a remote role; periodic travel to team and company events is required. The anticipated salary range for candidates for this role is $270,000 – $300,000. The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography. As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this [poster](https://www.e-verify.gov/sites/default/files/everify/images/manuals/EVParticipationPoster.JPG). Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. Show more [Apply now >](https://jobicy.com/jobs/161598-medical-director-clinical-developmentnephrology.md) * ![Upload CV](data:image/svg+xml;base64,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) ### Upload your resume now To unlock remote work opportunities and be discovered by global employers. This job listing has been manually reviewed by the Jobicy Trust & Safety Team for compliance with our posting guidelines, including verification of the company's legitimacy, accuracy of job details, clarity of remote work policy, and absence of misleading or fraudulent content. ## Role DNA A quick view of the complexity, pace, ownership and collaboration implied by the job description. ### Job Complexity 5/5EasyHard ### Pace & Pressure 5/5RelaxedFast-paced ### Autonomy Level 5/5GuidedFull ownership ### Communication Load 5/5IndependentCollaborative AI insightThis is a senior medical leadership position requiring an MD, nephrology expertise, clinical-development judgment, and responsibility for patient safety and scientific integrity. The role demands independent decisions across complex, regulated, cross-functional programs in a fast-paced biotech environment. ## Salary analysis Estimated compensation compared with the broader US market for similar roles. Estimated job median (per year)Market rate$285,000US market range (per year)$260k–$340k0$374.00k AI insightThe yearly pay period is inferred from the job context; it was not explicitly stated by the employer. The employer discloses a base salary range of USD 270,000 to USD 300,000. The annual cadence is inferred from the range, seniority, U.S. location context, and full-time professional role, rather than explicitly stated. The midpoint is USD 285,000 per year; an estimated U.S. market range for a Medical Director in clinical development with nephrology expertise is USD 260,000 to USD 340,000 per year. ## Core skills Skills and capabilities most closely associated with this opportunity. [Nephrology](https://jobicy.com/jobs?search_keywords=Nephrology.md)[Clinical Development](https://jobicy.com/jobs?search_keywords=Clinical%20Development.md)[Clinical Trial Design](https://jobicy.com/jobs?search_keywords=Clinical%20Trial%20Design.md)[Medical Monitoring](https://jobicy.com/jobs?search_keywords=Medical%20Monitoring.md)[Patient Safety](https://jobicy.com/jobs?search_keywords=Patient%20Safety.md)[Protocol Development](https://jobicy.com/jobs?search_keywords=Protocol%20Development.md)[Regulatory Affairs](https://jobicy.com/jobs?search_keywords=Regulatory%20Affairs.md)[IND Preparation](https://jobicy.com/jobs?search_keywords=IND%20Preparation.md)[NDA Preparation](https://jobicy.com/jobs?search_keywords=NDA%20Preparation.md)[Clinical Data Interpretation](https://jobicy.com/jobs?search_keywords=Clinical%20Data%20Interpretation.md)[Rare Disease Research](https://jobicy.com/jobs?search_keywords=Rare%20Disease%20Research.md)[Cross-functional Leadership](https://jobicy.com/jobs?search_keywords=Cross-functional%20Leadership.md)[KOL Engagement](https://jobicy.com/jobs?search_keywords=KOL%20Engagement.md)[Scientific Communication](https://jobicy.com/jobs?search_keywords=Scientific%20Communication.md) Sample interview questionsHow would you approach the design of a clinical trial for an immune-mediated kidney disease?I would begin with the target product profile, disease biology, unmet need, and available natural-history data. I would define a clinically meaningful patient population, appropriate endpoints, safety-monitoring plan, statistical assumptions, and operational feasibility, then align the protocol with regulatory expectations and input from investigators and patient advocates. Describe your approach to medical monitoring during an active clinical study. I establish clear safety-review processes, maintain rapid communication with sites and the clinical operations team, and assess eligibility, adverse events, protocol deviations, and emerging efficacy signals in context. My focus is protecting participants, maintaining scientific integrity, and ensuring that safety decisions are timely, well documented, and consistent with the protocol. How do you manage competing priorities across several clinical development projects? I prioritize work according to participant safety, regulatory deadlines, program critical path, and decision impact. I use transparent planning, define accountable owners and milestones, communicate risks early, and reassess priorities as new data or operational issues emerge. What would you contribute to interactions with regulatory authorities? I would provide clear medical and scientific rationale for development strategy, protocol choices, endpoints, and benefit-risk assessments. I would work closely with regulatory colleagues to prepare concise, evidence-based briefing materials and ensure that agency feedback is translated into practical program actions. How would you build productive relationships with nephrology KOLs and clinical investigators? I would engage them with scientific curiosity, transparency, and respect for their clinical expertise. I would seek input on disease burden, endpoint relevance, site feasibility, and patient experience while maintaining appropriate governance and ensuring that feedback improves the quality and execution of the clinical program. Next step ## Apply now. 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