Developmental Biologist Career Path Guide

A developmental biologist investigates the processes through which organisms grow and develop from a single cell to complex multicellular beings. They explore the genetic, molecular, and cellular mechanisms regulating development, contributing to fields like regenerative medicine, congenital disease research, and evolutionary biology. Their work combines laboratory experiments, data analysis, and collaboration across disciplines to unlock the mysteries behind life’s formation and progression.

8%

growth rate

$87,500

median salary

remote-friendly

πŸ“ˆ Market Demand

Low
High
High

The demand for developmental biologists is high, fueled by the expansion of biomedical research and the growing importance of regenerative medicine and genetic disease research. Biotechnology and pharmaceutical sectors actively seek experts to innovate therapeutic solutions and improve understanding of human development.

πŸ‡ΊπŸ‡Έ Annual Salary (US, USD)

55,000β€”120,000
Median: $87,500
Entry-Level
$64,750
Mid-Level
$87,500
Senior-Level
$110,250

Top 10% of earners in this field can expect salaries starting from $120,000+ per year, especially with specialized skills in high-demand areas.

Core Functions of the Developmental Biologist Role

Developmental biology is a dynamic and intricate field dedicated to understanding how living organisms grow, develop, and differentiate over time. Developmental biologists focus on the mechanisms governing cellular differentiation, tissue formation, and organogenesis, tracing how an organism progresses from a fertilized egg to a fully formed individual. This discipline sits at the nexus of genetics, molecular biology, cell biology, and evolutionary theory, ensuring robust insight into both normal development and the basis of developmental disorders.

Their research often involves studying model organisms such as fruit flies (Drosophila melanogaster), zebrafish, frogs, mice, and more recently, advances in stem cell research and organoids. By analyzing gene expression patterns, signaling pathways, and cellular interactions, developmental biologists identify the intricate choreography cells execute during embryonic, fetal, and postnatal development stages.

Applications of developmental biology extend far beyond academic curiosity. Insights gained from this research inform regenerative medicine, cancer biology, birth defect prevention, and aging. These scientists commonly contribute to creating innovative therapies involving tissue engineering and stem cell treatment aimed at repairing damaged organs or reversing degenerative diseases.

Daily work integrates laboratory-based investigations using advanced microscopy, genetic editing tools like CRISPR, and bioinformatics approaches to process high-throughput data. Collaboration with clinicians, bioengineers, and computational biologists is often critical for developing translational research projects. This role requires great precision, critical thinking, and a continuously adaptive learning approach as cutting-edge tools and scientific understanding evolve rapidly.

Key Responsibilities

  • Design and conduct experiments to study cellular and molecular mechanisms of development.
  • Analyze gene expression and regulation during various stages of organismal growth.
  • Utilize model organisms such as zebrafish, fruit flies, and mice to investigate developmental processes.
  • Employ advanced imaging techniques including confocal and fluorescence microscopy to visualize cell behavior.
  • Apply genetic engineering methods like CRISPR-Cas9 to manipulate genes and study their function.
  • Interpret complex biological data using biostatistics and bioinformatics software.
  • Collaborate with interdisciplinary teams including geneticists, clinicians, and computational scientists.
  • Develop protocols for stem cell culture and differentiation.
  • Contribute to scientific publications, grant proposals, and presentations.
  • Ensure laboratory safety and regulatory compliance for biological research.
  • Investigate developmental disorders and their genetic underpinnings.
  • Maintain detailed research documentation and laboratory notebooks.
  • Stay updated on latest scientific literature and technological advances.
  • Mentor junior researchers, students, and lab technicians.
  • Translate basic research findings into potential clinical applications and therapies.

Work Setting

Developmental biologists typically work in research laboratories found within universities, medical schools, government research institutions, and private biotech or pharmaceutical companies. The environment is generally controlled and sterile, featuring specialized equipment like microscopes, incubators, and cell culture facilities. Lab work can be meticulous, requiring attention to sterile techniques, precision pipetting, and consistent monitoring of experiments over long periods. Collaboration and communication with colleagues happen frequently, often in the form of lab meetings, seminars, and cross-disciplinary projects. Some fieldwork might be involved depending on the research species but is generally less common than benchwork. Work hours can be extended during critical experimental phases or when meeting publication deadlines. Despite the demanding nature, the lab environment fosters curiosity, innovation, and a strong community of scientific peers.

Tech Stack

  • CRISPR-Cas9 gene editing systems
  • Confocal microscopy
  • Fluorescence microscopy
  • Live-cell imaging platforms
  • Flow cytometry
  • Polymerase chain reaction (PCR) machines
  • Gel electrophoresis apparatus
  • Western blotting instruments
  • RNA sequencing (RNA-seq) technologies
  • Bioinformatics software (e.g., Galaxy, Bioconductor)
  • Cell culture hoods and incubators
  • Stem cell culture reagents and protocols
  • Micromanipulators
  • Microarrays
  • Spectrophotometers
  • Gene expression analysis tools
  • High-throughput screening platforms
  • Next-generation sequencing (NGS) systems
  • Image analysis software (e.g., ImageJ, Fiji)
  • Flow cytometers

Skills and Qualifications

Education Level

Becoming a developmental biologist generally requires an advanced educational background in biology or related life sciences. Most professionals start with a bachelor’s degree in biology, biochemistry, molecular biology, or a similar field, where foundational knowledge in genetics, cell biology, and physiology is built. Progressing into research typically necessitates earning a master’s degree and often a PhD focused specifically on developmental biology or a specialized area within molecular genetics or cell biology. Graduate studies emphasize hands-on laboratory training, advanced coursework in developmental theory and techniques, and original research culminating in a dissertation.

Postdoctoral fellowships are common to deepen expertise, establish an independent research profile, and gain experience with cutting-edge methodologies. These are crucial for building a competitive academic or industry research career. Depending on career goals, additional certifications in bioinformatics, microscopy, or specialized genetic analysis may be advantageous. Staying current through continuous professional development such as workshops, conferences, and scientific networking is essential due to the rapid advancements within this scientific field.

Tech Skills

  • Molecular cloning
  • Gene editing with CRISPR-Cas9
  • Microscopy (confocal, fluorescence, live imaging)
  • Cell culture and tissue culture techniques
  • Flow cytometry
  • Western blotting and immunohistochemistry
  • RNA extraction and quantitative PCR
  • Bioinformatics data analysis
  • Sequencing technologies (NGS, RNA-seq)
  • Protein expression analysis
  • Experimental design and statistical analysis
  • Fluorescent labeling and tagging
  • Micromanipulation techniques
  • Use of model organisms (Drosophila, zebrafish, mouse)
  • Stem cell culture and differentiation protocols

Soft Abilities

  • Critical thinking and analytical reasoning
  • Attention to detail
  • Effective scientific communication
  • Collaboration and teamwork
  • Problem-solving aptitude
  • Time management
  • Adaptability to new technologies
  • Patience and perseverance
  • Mentoring and leadership abilities
  • Scientific curiosity and creativity

Path to Developmental Biologist

Embarking on a career as a developmental biologist begins with obtaining a strong foundation in biological sciences through a bachelor's degree. Focus on coursework covering molecular biology, genetics, cell biology, and embryology. Engaging in undergraduate research projects or internships within laboratories that focus on developmental biology can provide invaluable hands-on experience and help solidify career interests.

Pursuing graduate education is a vital next step. Applications to master’s and doctoral programs should emphasize a clear research focus on developmental mechanisms or related fields. During graduate studies, prioritize gaining proficiency in laboratory techniques, research methodology, and experimental design. Publishing research findings and attending scientific conferences can build a professional network and boost future career prospects.

Postdoctoral research often serves as a bridge to independent investigator roles in academia or industry. Selecting fellowships in innovative labs with access to cutting-edge technology and multidisciplinary collaborations heightens skill development. The postdoc years provide critical training in leadership, grant writing, and project management.

Career progression frequently involves positioning oneself within research institutions, biotechnology firms, or pharmaceutical companies focusing on developmental biology applications such as regenerative medicine and genetic disease modeling. Continuous learning through workshops, certifications in bioinformatics or imaging technologies, and active engagement with professional societies ensures staying abreast of emerging trends and methods.

Required Education

The educational journey for developmental biologists typically begins with a bachelor's degree in biological sciences, biochemistry, or a related field. Undergraduate curricula cover foundational topics including genetics, molecular biology, cell biology, embryology, and physiology. Students are encouraged to participate in laboratory work or internships to acquire practical skills early on.

Graduate education is often essential for securing positions as lead researchers or scientific specialists. Master’s programs provide advanced coursework and focused research in developmental processes with opportunities to work alongside experienced scientists. Most students aiming for a research career continue toward a PhD, specializing in developmental biology, molecular genetics, or cellular biology. Doctoral studies require conducting original experiments, publishing results, and defending a dissertation that contributes new knowledge.

Postdoctoral training enhances specialization and research independence. These positions commonly last 2-5 years and provide experience applying novel techniques such as CRISPR gene editing or sophisticated imaging tools. Some postdocs may also pursue industry internships to diversify skills.

Professional development includes enrolling in workshops on bioinformatics or stem cell culture, attending national and international conferences like those hosted by the Society for Developmental Biology, and staying current through scientific journals. Certifications in data analysis software (e.g., R, Python for bioinformatics) or advanced microscopy enhance competitiveness.

For certain clinical or translational roles, additional training in biomedical sciences or health policy might be advantageous. A combination of deep scientific expertise, practical training, and soft skills developed through teaching or mentoring programs shapes well-rounded developmental biologists.

Career Path Tiers

Junior Developmental Biologist

Experience: 0-3 years

Often starting as a research technician or graduate student assistant, a junior developmental biologist supports experimental design and data collection under supervision. Responsibilities include preparing samples, conducting routine assays, and learning foundational research techniques such as PCR, microscopy, and cell culture. At this stage, gaining proficiency with laboratory protocols and beginning to analyze data are key priorities. Junior biologists contribute to team meetings, assist in maintaining lab organization, and may co-author research papers. Mentorship focuses on building technical skills and understanding the scientific method deeply.

Mid-level Developmental Biologist

Experience: 3-7 years

At this stage, professionals independently design and lead experiments, interpret complex data, and often supervise junior staff or students. They integrate molecular techniques with bioinformatics to investigate developmental pathways, contribute substantially to grant proposals, and present findings at scientific conferences. Mid-level biologists often collaborate interdepartmentally and may begin specializing in niche areas such as stem cell biology or developmental genetics. Leadership in managing lab workflows and participating actively in knowledge dissemination marks this career phase.

Senior Developmental Biologist / Principal Investigator

Experience: 7+ years

Senior developmental biologists lead independent research groups or projects, secure funding through competitive grants, and publish novel insights to the scientific community. They mentor graduate students, postdocs, and junior researchers while shaping strategic research directions. This role requires excellence in scientific innovation, interdisciplinary collaboration, and often administrative management within academic or corporate settings. Senior biologists influence policy, ethical frameworks, and application of developmental research toward therapeutic innovations.

Lead Scientist / Director of Developmental Biology

Experience: 10+ years

Leaders at this level define organizational research priorities, oversee multiple projects, and manage scientific teams at a departmental scale. They guide technology adoption, spearhead translational research initiatives, and liaise with external stakeholders, including funding agencies and industry partners. Strategic vision, fundraising expertise, and exceptional mentorship distinguish professionals in these roles. They frequently contribute to shaping scientific discourse nationally and internationally through advisory positions or editorial work.

Global Outlook

Developmental biology represents a globally collaborative and highly dynamic discipline. Research institutions in North America, Europe, and Asia dominate the landscape for funding and innovation, but opportunities are expanding worldwide. The United States remains a hub of academic and biotech activity, with eminent universities, pharmaceutical companies, and government-funded initiatives offering abundant positions and resources. Countries like Canada, Germany, the United Kingdom, and Sweden provide strong public and private support, with well-established research networks and access to cutting-edge technology.

Asia’s research ecosystem is growing rapidly, led by China, Japan, and Singapore. These regions invest heavily in regenerative medicine and genetic research, providing exciting prospects for developmental biologists seeking to work in emerging biotech hubs. Australia and New Zealand also show steady growth in developmental biology research, often focusing on unique biodiversity and model organism studies.

Global collaborations allow scientists to share datasets, cross-validate findings, and engage in multidisciplinary projects addressing human health and evolutionary questions at unprecedented scales. Virtual networking platforms, international conferences, and joint grant programs facilitate worldwide career mobility.

However, job availability may vary due to funding cycles, regional specializations, and immigration policies. Scientists often need flexibility in geographic relocation and cultural adaptability. Proficiency in English as the primary scientific language and cross-cultural communication become critical for engaging with diverse research communities. Those open to international fellowships or industry partnerships can leverage global opportunities for career advancement and broader scientific impact.

Job Market Today

Role Challenges

Developmental biology careers face significant challenges including competitive funding landscapes, pressure to publish high-impact research, and the rapid pace of technological innovation requiring continuous skill updates. Securing stable research grants has become more difficult due to increased competition and fluctuating governmental support, leading many scientists to navigate job insecurity. The multidisciplinary nature of the field can be daunting, necessitating mastery of diverse techniques from molecular genetics to computational biology. Additionally, transitioning discoveries from bench to bedside remains complex, often slowed by regulatory and ethical considerations. The reproducibility crisis in biomedical research also places added scrutiny on experimental rigor, compelling developmental biologists to adopt more transparent and robust methodologies.

Growth Paths

The emergence of sophisticated gene-editing technologies, advances in single-cell sequencing, and tissue engineering fuel significant growth potential in developmental biology. Expanding interest in regenerative medicine, organoid development, and personalized therapies opens multiple pathways beyond academia, including biotech startups and pharmaceutical research. Public awareness and investment in congenital diseases and developmental disorders drive demand for developmental biologists to translate findings into clinical solutions. Intersecting fields like synthetic biology and computational modeling continue to offer opportunities for cross-sector innovation. Funding agencies increasingly support interdisciplinary and translational projects, expanding the scope for scientists skilled in integrating biology with technology. The increasing emphasis on big data analysis and systems biology also opens roles within bioinformatics and data science, creating hybrid career options.

Industry Trends

Current trends highlight a surge in the application of CRISPR and other gene editing tools to probe developmental pathways precisely. The use of organoidsβ€”three-dimensional mini-organs grown from stem cellsβ€”is revolutionizing disease modeling and drug testing. Single-cell RNA sequencing enables unprecedented resolution of cell differentiation trajectories. Computational biology’s integration into developmental research helps manage and simulate complex datasets, pushing the boundaries of predictive modeling. Ethical considerations are increasingly at the forefront, especially in human embryo research and gene editing, prompting evolving regulatory frameworks. Collaborative research models spanning academia, healthcare, and industry reflect a trend toward translational science aimed at tangible health outcomes. Diversity and inclusion efforts are also gaining momentum, ensuring broader representation in research questions and workforce composition.

A Day in the Life

Morning (9:00 AM - 12:00 PM)

Focus: Experiment Preparation and Data Collection
  • Prepare reagents, culture media, and model organisms.
  • Set up microscopy imaging sessions for live-cell or fixed samples.
  • Perform molecular biology assays, such as PCR or western blotting.
  • Collect samples for sequencing or flow cytometry.
  • Attend lab meetings to discuss ongoing experiments and troubleshoot issues.

Afternoon (12:00 PM - 3:00 PM)

Focus: Data Analysis and Literature Review
  • Analyze imaging or sequencing data using bioinformatics tools.
  • Interpret gene expression patterns and developmental phenotypes.
  • Read and summarize recent scientific papers to stay updated on new discoveries.
  • Plan subsequent experiments based on current results and hypotheses.

Late Afternoon (3:00 PM - 6:00 PM)

Focus: Collaboration and Reporting
  • Meet with interdisciplinary teams including computational biologists and clinicians.
  • Present preliminary findings within research groups or departmental seminars.
  • Draft manuscripts, grant applications, or research reports.
  • Train junior lab members on protocols and experimental methods.

Work-Life Balance & Stress

Stress Level: Moderate

Balance Rating: Good

While the nature of experimental research can involve unpredictable hours, especially during critical phases or grant deadlines, developmental biologists generally maintain a good balance between work and personal life. The academic environment encourages flexible scheduling, and industry roles sometimes offer more structured hours. Job stress stems from funding pressures and the need for continuous learning, yet many professionals find the intellectual stimulation rewarding and motivating. Effective time management and a supportive lab culture contribute positively to sustaining healthy work-life integration.

Skill Map

This map outlines the core competencies and areas for growth in this profession, showing how foundational skills lead to specialized expertise.

Foundational Skills

The core scientific concepts and laboratory techniques every developmental biologist must master.

  • Molecular biology fundamentals
  • Genetic manipulation techniques
  • Microscopy and imaging
  • Cell culture methods
  • Experimental design and data analysis

Advanced Specializations

Specialized expertise that enables in-depth exploration of developmental processes and translational applications.

  • CRISPR gene editing
  • Stem cell and organoid culture
  • Single-cell RNA sequencing analysis
  • Computational biology and bioinformatics
  • Translational developmental therapeutics

Professional & Soft Skills

Complementary interpersonal and organizational skills essential for effective research and collaboration.

  • Scientific communication and writing
  • Project management
  • Interdisciplinary collaboration
  • Critical thinking
  • Mentorship and leadership

Pros & Cons for Developmental Biologist

βœ… Pros

  • Opportunity to contribute to groundbreaking scientific discoveries that impact human health.
  • Engagement with cutting-edge technology and methodologies.
  • Diverse career options in academia, industry, healthcare, and government sectors.
  • Collaboration with interdisciplinary teams fosters dynamic professional environments.
  • Potential to mentor and influence future generations of scientists.
  • Ability to pursue questions driven by intellectual curiosity and societal needs.

❌ Cons

  • Highly competitive funding environment leading to job instability.
  • Extended periods spent on repetitive experimental work.
  • Long training paths with significant educational requirements.
  • Pressure to publish regularly can lead to workplace stress.
  • Ethical and regulatory complexities surrounding human developmental research.
  • Limited remote work options due to hands-on laboratory requirements.

Common Mistakes of Beginners

  • Underestimating the importance of mastering fundamental laboratory techniques before advancing to complex experiments.
  • Failing to maintain meticulous and organized laboratory notebooks, leading to reproducibility issues.
  • Neglecting bioinformatics skills critical for analyzing large, complex datasets.
  • Overlooking the need for strong communication skills to convey findings effectively.
  • Rushing experiments without adequate planning or controls, risking invalid results.
  • Ignoring the value of interdisciplinary collaboration and networking.
  • Insufficient focus on troubleshooting skills to resolve common experimental failures.
  • Delayed engagement with professional development activities such as conferences and workshops.

Contextual Advice

  • Invest significant time early in your career to become proficient with core wet lab techniques before specializing.
  • Develop bioinformatics and programming skills alongside traditional experimental expertise.
  • Prioritize clear scientific communication, including writing and oral presentations.
  • Seek mentorship actively and participate in collaborative research environments.
  • Be patient and persistent; experimental research often involves trial, error, and iteration.
  • Stay current with emerging technologies and methods by attending relevant workshops.
  • Balance experimental work with reading literature to identify research gaps and opportunities.
  • Consider cross-training in complementary fields such as computational biology or regenerative medicine.

Examples and Case Studies

CRISPR Gene Editing to Study Limb Regeneration

A team of developmental biologists used CRISPR technology to knock out specific genes in zebrafish to understand mechanisms behind limb regeneration. By selectively disabling signaling pathways believed to drive regrowth, they identified critical genes that mediate tissue repair. The experiments involved precise gene editing, imaging regenerative growth stages, and transcriptomic profiling to uncover gene expression changes.

Key Takeaway: Integrating powerful genetic tools with classic developmental models can reveal fundamental insights into regenerative biology with potential translational impact in medicine.

Modeling Congenital Heart Defects Using Stem Cell-Derived Organoids

Researchers developed human cardiac organoids from pluripotent stem cells to replicate early heart development. By introducing mutations associated with congenital heart disease, they observed abnormal tissue organization and gene expression patterns. This approach provided a human-relevant system for studying developmental disorders inaccessible in vivo and enabled drug screening to identify potential therapies.

Key Takeaway: Organoid technology bridges developmental biology with clinical research, offering personalized models to investigate genetic diseases and therapeutic interventions.

Single-Cell Transcriptomics Illuminates Neural Crest Cell Differentiation

Employing single-cell RNA sequencing, scientists mapped the differentiation trajectories of neural crest cells during vertebrate embryogenesis. This high-resolution data helped delineate subpopulations and identify previously unknown intermediate cell states. The study combined computational analysis with embryological techniques to validate findings, advancing understanding of complex cell fate decisions.

Key Takeaway: Coupling single-cell technologies with developmental systems provides unprecedented detail of lineage specification, reshaping fundamental concepts of developmental biology.

Portfolio Tips

A strong developmental biology portfolio must showcase a balance between technical expertise, scientific creativity, and tangible research contributions. Start by documenting all laboratory techniques you have mastered, highlighting any specialized skills such as gene editing, stem cell culture, or advanced microscopy. Include detailed descriptions of your experimental projects emphasizing hypothesis-driven research, methodologies applied, and results obtained.

Publications, posters, and presentations form the core of your research profile. Ensure your CV and portfolio clearly reference peer-reviewed articles, collaborative projects, and any awards or recognitions. Including figures or visual summaries from your workβ€”such as imaging data or graphsβ€”can enhance the portfolio's impact. Demonstrate your ability to analyze complex data sets by including examples of bioinformatics or statistical analyses you performed.

Highlight interdisciplinary collaborations, mentoring experiences, and participation in scientific communities, such as societies or conference panels. For job or academic applications, tailor your portfolio to the audience and role by emphasizing relevant research topics and transferable skills.

An online presence through a personal website or platforms like ResearchGate and LinkedIn can supplement your portfolio, offering easier access for hiring committees and fostering professional connections. Continually update and curate your documents to reflect new accomplishments and emerging skills. Clear organization, professional formatting, and thoughtful annotation of materials illustrate your commitment to scientific rigor and communication excellence.

Job Outlook & Related Roles

Growth Rate: 8%
Status: Growing much faster than average
Source: U.S. Bureau of Labor Statistics

Related Roles

Frequently Asked Questions

What specific model organisms are most commonly used in developmental biology research?

Model organisms such as fruit flies (Drosophila melanogaster), zebrafish (Danio rerio), frogs (Xenopus laevis), and mice (Mus musculus) are frequently used due to their well-characterized genetics, ease of manipulation, and relevance to human development. Each model offers unique advantages, such as rapid development cycles or transparent embryos, facilitating observation of developmental processes.

How important is bioinformatics knowledge for a developmental biologist?

Bioinformatics skills are increasingly essential. Analyzing gene expression data, genome editing outcomes, and single-cell sequencing requires competence with computational tools and statistical software. Basic programming literacy (e.g., in R or Python) enhances data interpretation capabilities and makes a developmental biologist more versatile and competitive.

Can developmental biology research lead to clinical applications?

Yes, research in developmental biology underpins many translational efforts such as regenerative medicine, congenital disease diagnosis, and gene therapy development. Understanding how cells differentiate and organs form helps design strategies to repair damaged tissues or correct developmental defects, bridging basic science and medical therapies.

What are common career alternatives if I don’t want to pursue academia?

Outside academia, developmental biologists find roles in the biotechnology and pharmaceutical industries, primarily in research and development. Opportunities exist in science communication, patent law (with additional training), regulatory affairs, and bioinformatics. Some also transition into teaching at various levels or scientific consulting.

Is a postdoctoral fellowship mandatory to advance in this field?

While not absolutely mandatory, postdoctoral fellowships are highly recommended, especially for those targeting independent research or faculty positions. Postdocs provide valuable experience in experimental design, grant writing, and leadership, helping to build a strong research portfolio and professional network.

How competitive is securing funding for developmental biology research?

Competition for funding can be intense due to limited resources and a growing number of applicants. Successful candidates often have strong publication records, clear research aims, and collaborations. Diversifying funding sources, such as government grants, foundations, and industry partnerships, helps mitigate challenges.

What is the typical daily work setting for a developmental biologist?

Most daily work takes place in laboratories equipped with specialized instruments for cell culture, microscopy, and molecular assays. Activities range from hands-on experiments and data analysis to team meetings and literature review. Fieldwork is rare but possible depending on research focus.

Are there ethical concerns specific to developmental biology research?

Ethical considerations arise particularly in research involving human embryos, gene editing, and animal models. Researchers must adhere to strict institutional review board (IRB) protocols and legal regulations to ensure responsible conduct. Debates around manipulating human developmental stages and gene editing warrant ongoing ethical scrutiny.

Sources & References

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