The U.S. Chamber of Commerce was founded in 1912 as a non-profit membership organization representing the unified interests of U.S. businesses across diverse sectors. It is the world’s largest business federation, representing nearly three million companies, 2,800 state and local chambers, 830 business associations, and over 100 American Chambers of Commerce abroad.

Headquartered in Washington, D.C., across Lafayette Square from the White House, the Chamber pursues its mission to advocate for business and free enterprise interests before Congress, the White House, regulatory agencies, courts, and governments globally. The organization serves as a powerful voice for business policy and economic growth in the United States and internationally.

The U.S. Chamber engages with numerous stakeholders including government officials, business leaders, and the public to promote pro-business policies and a competitive economic environment. It provides various services to its members, including advocacy, networking opportunities, and resources for business development.

Its headquarters at 1615 H Street NW is a historic building reflecting its long-standing presence in American commerce and public policy. The Chamber also supports regional offices to extend its reach and enhance engagement with local and state business communities.

In addition to advocacy, the Chamber undertakes efforts to support small and medium-sized businesses, foster innovation, and address emerging economic challenges. It is committed to creating an environment where businesses can thrive, thereby contributing to job creation and economic prosperity nationwide.