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Associate Director, Product Management, Oncology Clinical Trial Matching

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Remote from
USA
Salary
USD 174,700–210,400 / yr
Employment
Full Time
Experience
Director
Published
Apply before
4 Nov 2026
Listing views
16
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0
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AI Summary

The role, at a glance.

Natera is seeking an Associate Director of Product Management to lead strategy, development, commercialization, and lifecycle management for Signatera oncology clinical-trial matching products. The role owns the product roadmap, translates customer and operational needs into requirements, and uses performance data to improve enrollment and product outcomes. It requires close leadership across R&D, software engineering, clinical and medical teams, operations, regulatory, sales, marketing, and business development. Candidates need substantial product-management or commercialization experience, ideally in oncology diagnostics, medical devices, molecular testing, or life sciences. The position is a US-remote, senior individual-contributor/functional-lead role with significant strategic visibility and stakeholder influence.

Role DNA

A quick view of the complexity, pace, ownership and collaboration implied by the job description.

Job Complexity

5/5
EasyHard

Pace & Pressure

5/5
RelaxedFast-paced

Autonomy Level

5/5
GuidedFull ownership

Communication Load

5/5
IndependentCollaborative
AI insightThis is a senior, highly cross-functional product leadership position in a regulated oncology diagnostics environment. Success requires balancing long-range strategy with detailed execution, scientific and commercial fluency, and influence across senior stakeholders.

Salary analysis

Estimated compensation compared with the broader US market for similar roles.

Estimated job medianMarket rate
$192,550
US market range$165k–$225k
AI insightThe disclosed US pay range is $174,700 to $210,400 USD, with a midpoint of $192,550. This is a competitive annual base-pay range for an Associate Director of Product Management in US oncology diagnostics and life sciences; the estimated broader US market range is approximately $165,000 to $225,000 annually, depending on diagnostics expertise, location, and scope of product ownership.

Core skills

Skills and capabilities most closely associated with this opportunity.

Sample interview questions
How would you build a product roadmap for a clinical trial matching product in oncology?

I would begin with patient, provider, sponsor, and operational workflows; validate unmet needs through VOC research; and assess market, regulatory, technical, and laboratory constraints. I would prioritize opportunities using expected patient and business impact, feasibility, risk, and strategic alignment, then define measurable outcomes such as trial-match quality, enrollment conversion, turnaround time, and adoption.

Describe how you would align R&D, software, clinical, operations, and commercial teams around a complex product initiative.

I would establish a shared problem statement, product vision, success metrics, decision rights, and a transparent operating cadence. Regular roadmap reviews, documented requirements, dependency tracking, and data-based trade-off discussions help each function understand its role while keeping decisions centered on customer and patient value.

What metrics would you use to evaluate the performance of a clinical trial matching product?

I would track eligible-patient identification rate, match precision and recall where measurable, referral and enrollment conversion, time from test result to match, user adoption, customer satisfaction, operational turnaround time, and sponsor or site engagement. I would segment results by tumor type, care setting, and workflow to identify specific improvement opportunities.

How do you use Voice of Customer research when defining product requirements?

I use structured interviews, workflow observation, surveys, and support or sales feedback to distinguish stated preferences from underlying jobs to be done. I synthesize themes with quantitative evidence, validate them with representative users, and convert the highest-value problems into clear requirements, acceptance criteria, and outcome metrics.

How would you make a business case for investing in a new oncology product capability?

I would quantify the target customer problem, addressable market, expected adoption, revenue or strategic value, implementation cost, and ongoing operating requirements. I would model multiple scenarios, identify assumptions and risks, include clinical and regulatory considerations, and recommend a phased investment plan with milestones that can validate value before full-scale rollout.

This analysis is generated from the job description. Salary estimates, role characteristics and sample answers are guidance, not employer-provided facts.
Opportunity details

About this role.

Position Summary: The Associate Director of Product Management, Oncology, leads the development and commercialization of Signatera clinical trial matching products and services for current and future versions of the Signatera product line, including on-market and new tissue-informed MRD products. This role supports the long-term vision and 5-year strategic planning for the product roadmap, with a focus on growing and accelerating the Signatera trials enrollment. The position requires strategic thinking combined with strong execution and leadership in cross-functional teams. Responsibilities include managing the product lifecycle from concept to obsolescence, developing the strategic roadmap, prioritizing features and programs, creating product requirements, and improving overall product performance.

Primary Responsibilities:

  • Develop and execute the clinical trial matching product roadmap for the Signatera product line.
  • Define and deliver product requirements based on customer needs and operational constraints.
  • Oversee product performance and manage product support across various departments, including Product Management, Molecular Biology R&D, Software Engineering, Sales & Marketing, Clinical/Medical, Operations, Regulatory, and Business Development.
  • Develop product performance metrics, analyze data, and collaborate with teams to identify and implement improvement strategies.
  • Identify business opportunities, create business cases, and build financial models to support product initiatives.
  • Conduct Voice of Customer (VOC) interviews, market research, and competitive analysis to validate product features and enhance customer satisfaction.
  • Collaborate with marketing teams to define product positioning, market launch plans, pricing, and the creation of key marketing collateral.
  • Present data-driven arguments to gain stakeholder alignment and buy-in for strategic initiatives.
  • Provide regular updates to both internal and external stakeholders on product vision, progress, and roadmap updates.

Qualifications:

  • Bachelor’s degree required, preferably in physical or life sciences, statistics, or engineering. A Master’s or PhD degree is preferred.
  • A minimum of 7 years of experience, with at least 5 years in product management, product marketing, commercialization, or strategic consulting.
  • Experience in oncology products, medical devices, or diagnostics is highly preferred.
  • Familiarity with large-scale high complexity molecular testing laboratories, particularly in tumor tissue sequencing, is desirable.
  • Expertise in the Life Sciences industry is highly preferred.

Knowledge, Skills, and Abilities:

  • Proven ability to lead and motivate cross-functional teams.
  • Strong understanding of technology and the ability to articulate customer value propositions effectively.
  • Excellent project and process management skills.
  • Proficiency with office applications (e.g., MS Word, MS Excel) and presentation tools (e.g., MS PowerPoint).
  • Basic financial and economic modeling skills.
  • Exceptional communication skills, both written and verbal.
  • Strong organizational skills and attention to detail, with the ability to manage multiple tasks simultaneously.
  • Candidates with experience leading scientific or technical projects in R&D roles are encouraged to apply.
  • Must demonstrate strong analytical, product development, and project management expertise.
  • Ability to collaborate effectively across functions and influence decision-making in a team environment.
  • Ability to communicate regularly with senior leadership.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$174,700—$210,400 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits – Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
– BBB announcement on job scams
– FBI Cyber Crime resource page

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This job listing has been manually reviewed by the Jobicy Trust & Safety Team for compliance with our posting guidelines, including verification of the company's legitimacy, accuracy of job details, clarity of remote work policy, and absence of misleading or fraudulent content.

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