About this role.
The Change Order Manager develops and validates budgetary change orders for clinical-trial projects, translating revised assumptions, resourcing, timelines, and service requirements into accurate financial documentation. The role works closely with project managers, functional leads, financial analysts, vendors, and clients to resolve information gaps and present clear variance analyses. It also owns change-order tracking, supports departmental metrics, and leads alignment calls to ensure timely delivery. Success requires advanced Excel-based costing, financial rigor, strong written documentation, and familiarity with CRO or clinical-research project lifecycles.
Role DNA
A quick view of the complexity, pace, ownership and collaboration implied by the job description.
Job Complexity
4/5Pace & Pressure
4/5Autonomy Level
4/5Communication Load
5/5Salary analysis
Estimated compensation compared with the broader US market for similar roles.
Core skills
Skills and capabilities most closely associated with this opportunity.
Sample interview questions
I begin by documenting each revised assumption and mapping it to affected scope, timelines, countries, sites, patients, resourcing, and vendor services. I validate the inputs with functional owners, use controlled Excel formulas and cross-checks, compare the revision to the prior approved budget, and clearly explain all deltas in the client-facing narrative.
I would identify the exact discrepancy, quantify its potential budget or timeline impact, and convene a focused alignment discussion with the relevant owners. I would document the agreed assumption, retain an audit trail of the decision, and avoid finalizing the change order until the input is reconciled or an authorized decision-maker accepts the stated risk.
I use formula audits, independent recalculation of key drivers, reasonableness testing against historical or baseline costs, checks for links and hard-coded values, and reconciliation of totals to detailed line items. I also review version control and ensure that all narrative assumptions match the final financial model.
I would present a concise summary of the change, followed by a transparent breakdown of the specific drivers, such as scope expansion, enrollment changes, country additions, timeline shifts, or revised resourcing. I would use plain language, connect each cost to the underlying assumption, and be ready to discuss alternatives or the impact of different scenarios.
I assess each request by contractual deadline, client impact, financial materiality, project risk, and completeness of inputs. I establish a visible tracker, communicate dependencies and expected delivery dates early, schedule alignment calls for unresolved items, and protect time for quality review before submission.
Position Summary:
The Change Order Manager will lead change order budget creation activities between project management, functional leads, and the financial analysts in order to develop, explain, and provide variance analysis for the change orders in preparation for presentation to the client. The Change Order Manager will contribute to the tracking and record keeping of change order requests in order to develop departmental metrics, and lead and/or actively participate in internal and client calls on a routine basis.
Essential functions of the job include but are not limited to:
• Work collaboratively with project management, financial analysts, functional leads, and other contributing parties in order to produce a high-quality change order which is meaningful, accurate, and in accordance with the changes in assumptions on a timely basis.
• Provide review of changes in assumptions to the budget in order to work with the extended project team to identify information gaps and/or discrepancies, unique service requirements in order to translate information into budgets.
• Actively communicate with the project team and other key stakeholders both within and outside the organization in order to support the timely and accurate delivery of change orders.
• Schedule and lead the change order alignment calls with the extended project team.
• Prepare, edit, and customize change order text to accurately reflect the strategic message, changes in assumptions, budget summaries, changes in resourcing, and additional financial requirements.
• Incorporate vendor and partner change orders into the main change order as applicable while ensuring accuracy and completeness.
• Ensure all information is accurate and clearly stated including assumptions, processes described, changes from prior executed agreements inclusive of resourcing updates, timeline shifts, country/site/patient changes, etc.
• Meticulous attention to the use of financial formulas to ensure an accurate change order which includes, but not limited to: cross checks, formula review, reasonable testing, etc.
Qualifications:
Minimum Required:
• Bachelor’s degree or equivalent in science, finance/accounting or related business field.
Other Required:
• A minimum of 5 years’ experience in proposal and/or change order preparation in an excel based costing tool and preparation of change order/contract documents
• Working knowledge of project budgets, financial analysis, advanced excel skills with a meticulous attention to detail.
Preferred:
• MBA Preferred
• Experience in the CRO industry
Competencies:
• Working knowledge of the life cycle of a project with a solid foundation of how the changes in assumptions impact the costings/budget and financial impact at each stage of the clinical trial.
• Strong Excel/Microsoft Office skills and ability to thrive in a multi-tasking environment.
• Strong financial skills combined with an attention and appreciation to detail.
• High energy and enthusiasm with a strong commitment to exceeding expectations.
• Flexibility and willingness to work on multiple assignments of varying tasks with personnel throughout the organization.
• Ability to learn quickly. Good oral and written communication & interpersonal skills with the ability to connect and build relationships with management and others throughout the organization.
• Exhibits self-motivation and is able to work and plan independently as well as in a team environment.
• Team player with a desire to be an active, long-term participant in the growth of the company.
Travel required
• Travel will be minimal.
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Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.
If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at myHR@precisionmedicinegrp.com.
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Annual salary information is not provided for this position. Explore salary ranges for similar roles in our Salary Directory ›
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